MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma

OBJECTIVE: To investigate the effects of mTOR inhibition on drug resistance in lung adenocarcinoma after combined radiation and erlotinib therapy. RESULTS: Combined radiation and erlotinib therapy produced clear radiosensitization effects both in vitro and in vivo; however, tumor cells remained drug...

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Pubblicato in:Oncotarget
Autori principali: Zhuang, Hongqing, Bai, Jing, Chang, Joe Y., Yuan, Zhiyong, Wang, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356691/
https://ncbi.nlm.nih.gov/pubmed/27713162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12423
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