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Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma

Dicer, a key component of the microRNA processing machinery, has been reported to exert discrepant prognostic values and biological roles in different types of cancers. Here, we investigated the function and prognostic value of Dicer in clear cell renal cell carcinoma (ccRCC). Using the retrospectiv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yan-Su, Meng, Fei, Li, Hai-Long, Liu, Qing-Hua, Hou, Ping-Fu, Bai, Jin, Zheng, Jun-Nian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356663/
https://ncbi.nlm.nih.gov/pubmed/27732931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12520
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