Pathological complete response after cisplatin neoadjuvant therapy is associated with the downregulation of DNA repair genes in BRCA1-associated triple-negative breast cancers

Pathologic complete response (pCR) after neoadjuvant chemotherapy is considered a suitable surrogate marker of treatment efficacy in patients with triple-negative breast cancers (TNBCs). However, the molecular mechanisms underlying pCR as a result of such treatment remain obscure. Using real-time PC...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Domagala, Pawel, Hybiak, Jolanta, Rys, Janusz, Byrski, Tomasz, Cybulski, Cezary, Lubinski, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356581/
https://ncbi.nlm.nih.gov/pubmed/27626685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11900
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