Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc(Min/+) model

Hepatocyte growth factor activator inhibitor type 1 (HAI-1), encoded by the Spint1 gene, is a membrane-bound serine protease inhibitor expressed on the epithelial cell surface. We have previously reported that the intestine-specific Spint1-deleted Apc(Min/+) mice showed accelerated formation of inte...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kawaguchi, Makiko, Yamamoto, Koji, Kanemaru, Ai, Tanaka, Hiroyuki, Umezawa, Kazuo, Fukushima, Tsuyoshi, Kataoka, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356577/
https://ncbi.nlm.nih.gov/pubmed/27612426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11863
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