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Protecting microRNAs from RNase degradation with steric DNA nanostructures

Tumor suppressive microRNAs are potent molecules that might cure cancer, one day. Despite the many advanced strategies for delivery of these microRNAs to the cell, there are few therapeutic microRNAs in clinical use. Progress in microRNA bioapplications is hindered by a high vulnerability of exogene...

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Publicat a:Chem Sci
Autors principals: Qian, H., Tay, C. Y., Setyawati, M. I., Chia, S. L., Lee, D. S., Leong, D. T.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356501/
https://ncbi.nlm.nih.gov/pubmed/28451245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01829g
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