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A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism

Unlike most bacteria, mycobacteria rely on the multi-domain enzyme eukaryote-like fatty acid synthase I (FAS I) to make fatty acids de novo. These metabolites are precursors of the biosynthesis of most of the lipids present both in the complex mycobacteria cell wall and in the storage lipids inside...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Cabruja, Matías, Mondino, Sonia, Tsai, Yi Ting, Lara, Julia, Gramajo, Hugo, Gago, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356441/
https://ncbi.nlm.nih.gov/pubmed/28228470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160277
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