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Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

BACKGROUND: Axonal damage and loss substantially contribute to the incremental accumulation of clinical disability in progressive multiple sclerosis. Here, we assessed the amount of Wallerian degeneration in brain tissue of multiple sclerosis patients in relation to demyelinating lesion activity and...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Singh, Shailender, Dallenga, Tobias, Winkler, Anne, Roemer, Shanu, Maruschak, Brigitte, Siebert, Heike, Brück, Wolfgang, Stadelmann, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356322/
https://ncbi.nlm.nih.gov/pubmed/28302146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0831-8
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