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Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity
BACKGROUND: Bitter taste receptors (T2R) have recently been demonstrated to contribute to sinonasal innate immunity. One T2R, T2R38, regulates mucosal defense against gram-negative organisms through nitric oxide (NO) production, which enhances mucociliary clearance and directly kills bacteria. To de...
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| 出版年: | Am J Rhinol Allergy |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
OceanSide Publications, Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356199/ https://ncbi.nlm.nih.gov/pubmed/28452704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2500/ajra.2017.31.4424 |
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