Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin‐Dependent Effects on Platelet Aggregation Pathways

Genetic variation in the platelet endothelial aggregation receptor 1 (PEAR1) gene, most notably rs12041331, is implicated in altered on‐aspirin platelet aggregation and increased cardiovascular event risk. We prospectively tested the effects of aspirin administration at commonly prescribed doses (81...

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Dettagli Bibliografici
Pubblicato in:Clin Transl Sci
Autori principali: Backman, JD, Yerges‐Armstrong, LM, Horenstein, RB, Newcomer, S, Shaub, S, Morrisey, M, Donnelly, P, Drolet, M, Tanner, K, Pavlovich, MA, O'Connell, JR, Mitchell, BD, Lewis, JP
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355965/
https://ncbi.nlm.nih.gov/pubmed/28075528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12438
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