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Rho kinase II interference by small hairpin RNA ameliorates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

Novel therapeutic targets are required for the treatment of Parkinson's disease (PD). Previous studies suggest that the Rho/Rho-associated, coiled-coil-containing protein kinases (ROCKs) signaling pathway may be a promising therapeutic target in PD. To elucidate the importance of ROCKII in the...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhang, Qiong, Zhao, Yong-Fei, Xi, Jian-Ying, Yu, Wen-Bo, Xiao, Bao-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355756/
https://ncbi.nlm.nih.gov/pubmed/27840922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5889
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