Oxymatrine inhibits the migration of human colorectal carcinoma RKO cells via inhibition of PAI-1 and the TGF-β1/Smad signaling pathway

Transforming growth factor-β1 (TGF-β1) signaling has been shown to play a critical role in the development of epithelial-mesenchymal transition (EMT). PAI-1 is one of the most important target genes in the TGF-β/Smad signaling pathway, which can hinder the degradation of ECM composition and may prom...

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Bibliografische gegevens
Gepubliceerd in:Oncol Rep
Hoofdauteurs: Wang, Xiaoyu, Liu, Chun, Wang, Jiaqi, Fan, Yue, Wang, Zhenghua, Wang, Yuanyuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2017
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355745/
https://ncbi.nlm.nih.gov/pubmed/27959430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5292
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