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Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats

Previous studies have identified that dexmedetomidine (DEX) treatment can ameliorate the acute lung injury (ALI) induced by lipopolysaccharide and ischemia-reperfusion. However, the molecular mechanisms by which DEX ameliorates lung injury remain unclear. The present study investigated whether DEX,...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Fu, Chunlai, Dai, Xingui, Yang, You, Lin, Mengxiang, Cai, Yeping, Cai, Shaoxi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355722/
https://ncbi.nlm.nih.gov/pubmed/27959438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.6012
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