Early VEGF inhibition attenuates blood-brain barrier disruption in ischemic rat brains by regulating the expression of MMPs

Vascular endothelial growth factor (VEGF) inhibition has been demonstrated to be an effective strategy in preserving the integrity of the blood-brain barrier (BBB) in patients with acute ischemic stroke. Loss of the BBB is the key event associated with morbidity and mortality in these patients. Howe...

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Vydáno v:Mol Med Rep
Hlavní autoři: Zhang, Hai-Tao, Zhang, Ping, Gao, Yi, Li, Chen-Long, Wang, Hong-Jun, Chen, Ling-Chao, Feng, Yan, Li, Rui-Yan, Li, Yong-Li, Jiang, Chuan-Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355683/
https://ncbi.nlm.nih.gov/pubmed/27909732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5974
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