Hepatitis B virus X protein sensitizes HL-7702 cells to oxidative stress-induced apoptosis through modulation of the mitochondrial permeability transition pore

Chronic hepatitis B virus (HBV) infection is a leading cause of liver cirrhosis and cancer. Among the pathogenic factors of HBV, HBV X protein (HBx) is attracting increased attention. Although it is documented that HBx is a multifunctional regulator that modulates cell inflammation and apoptosis, th...

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Veröffentlicht in:Oncol Rep
Hauptverfasser: Gao, Wen-Yu, Li, Dan, Cai, De-En, Huang, Xiao-Yun, Zheng, Bi-Yun, Huang, Yue-Hong, Chen, Zhi-Xin, Wang, Xiao-Zhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355673/
https://ncbi.nlm.nih.gov/pubmed/27840960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5225
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