Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons

Neurons communicate by regulated secretion of chemical signals from synaptic vesicles (SVs) and dense-core vesicles (DCVs). Here, we investigated the maturation of these two secretory pathways in micro-networks of human iPSC-derived neurons. These micro-networks abundantly expressed endogenous SV an...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Emperador Melero, Javier, Nadadhur, Aishwarya G., Schut, Desiree, Weering, Jan V., Heine, Vivi M., Toonen, Ruud F., Verhage, Matthijs
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355645/
https://ncbi.nlm.nih.gov/pubmed/28238793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.019
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