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Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes

Changes in oocyte quality can have great impact on the developmental potential of early embryos. Here we test whether nuclear genome transfer from a developmentally incompetent to a developmentally competent oocyte can restore developmental potential. Using in vitro oocyte aging as a model system we...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Yamada, Mitsutoshi, Egli, Dieter
Format: Artigo
Language:Inglês
Published: Elsevier 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355644/
https://ncbi.nlm.nih.gov/pubmed/28242217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.020
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