The Pseudorabies Virus Glycoprotein gE/gI Complex Suppresses Type I Interferon Production by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDC) play a central role in the antiviral immune response, both in the innate response and in shaping the adaptive response, mainly because of their ability to produce massive amounts of type I interferon (TI-IFN). Here, we report that cells infected with the live atten...

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Vydáno v:J Virol
Hlavní autoři: Lamote, Jochen A. S., Kestens, Manon, Van Waesberghe, Cliff, Delva, Jonas, De Pelsmaeker, Steffi, Devriendt, Bert, Favoreel, Herman W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355608/
https://ncbi.nlm.nih.gov/pubmed/28122975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02276-16
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