The Pseudorabies Virus Glycoprotein gE/gI Complex Suppresses Type I Interferon Production by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDC) play a central role in the antiviral immune response, both in the innate response and in shaping the adaptive response, mainly because of their ability to produce massive amounts of type I interferon (TI-IFN). Here, we report that cells infected with the live atten...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Lamote, Jochen A. S., Kestens, Manon, Van Waesberghe, Cliff, Delva, Jonas, De Pelsmaeker, Steffi, Devriendt, Bert, Favoreel, Herman W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355608/
https://ncbi.nlm.nih.gov/pubmed/28122975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02276-16
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