Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice

Two populations of oligodendrogenic progenitors co-exist within the corpus callosum (CC) of the adult mouse. Local, parenchymal oligodendrocyte progenitor cells (pOPCs) and progenitors generated in the subependymal zone (SEZ) cytogenic niche. pOPCs are committed perinatally and retain their numbers...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Kazanis, Ilias, Evans, Kimberley A., Andreopoulou, Evangelia, Dimitriou, Christina, Koutsakis, Christos, Karadottir, Ragnhildur Thora, Franklin, Robin J.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355571/
https://ncbi.nlm.nih.gov/pubmed/28196689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.007
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