Divergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis

In the process of generating presumably clonal human induced pluripotent stem cells (hiPSCs) from two carriers of a complex structural rearrangement, each having a psychotic disorder, we also serendipitously generated isogenic non-carrier control hiPSCs, finding that the rearrangement occurs as an e...

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Publié dans:Stem Cell Reports
Auteurs principaux: TCW, Julia, Carvalho, Claudia M.B., Yuan, Bo, Gu, Shen, Altheimer, Alyssa N., McCarthy, Shane, Malhotra, Dheeraj, Sebat, Jonathan, Siegel, Arthur J., Rudolph, Uwe, Lupski, James R., Levy, Deborah L., Brennand, Kristen J.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
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Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355568/
https://ncbi.nlm.nih.gov/pubmed/28216146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.010
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