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An overview of pharmacodynamic modelling, ligand-binding approach and its application in clinical practice

The study of the magnitude and variation of drug response is defined as pharmacodynamics (PDs). PD models examine plasma concentration and effect relationship. It can predict the archetypal effect ([Formula: see text]) of a drug as a function of the drug concentration ([Formula: see text]) and estim...

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Bibliografiske detaljer
Udgivet i:Saudi Pharm J
Main Authors: Salahudeen, Mohammed Saji, Nishtala, Prasad S.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355565/
https://ncbi.nlm.nih.gov/pubmed/28344466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2016.07.002
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