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Prolonged exposure of colon cancer cells to 5-fluorouracil nanoparticles improves its anticancer activity

In this study, we aimed to improve the anticancer effect of 5-FU on human colon cancer cell lines by incorporating in poly(d,l lactic-co-glycolic acid) (PLGA) nanoparticles (NPs). The 5-FU-PLGA NPs were prepared by nanoprecipitation technique. Prepared NPs were moderately dispersed with an average d...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Tawfik, Essam, Ahamed, Maqusood, Almalik, Abdulaziz, Alfaqeeh, Mohammad, Alshamsan, Aws
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355554/
https://ncbi.nlm.nih.gov/pubmed/28344470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2016.05.010
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