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Role of Pore-Lining Residues in Defining the Rate of Water Conduction by Aquaporin-0

Compared to other aquaporins (AQPs), lens-specific AQP0 is a poor water channel, and its permeability was reported to be pH-dependent. To date, most water conduction studies on AQP0 were performed on protein expressed in Xenopus oocytes, and the results may therefore also reflect effects introduced...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Saboe, Patrick O., Rapisarda, Chiara, Kaptan, Shreyas, Hsiao, Yu-Shan, Summers, Samantha R., De Zorzi, Rita, Dukovski, Danijela, Yu, Jiaheng, de Groot, Bert L., Kumar, Manish, Walz, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355496/
https://ncbi.nlm.nih.gov/pubmed/28297654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.01.026
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