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Inferring Mechanistic Parameters from Amyloid Formation Kinetics by Approximate Bayesian Computation
Amyloid formation is implicated in a number of human diseases, and is thought to proceed via a nucleation-dependent polymerization mechanism. Experimenters often wish to relate changes in amyloid formation kinetics, for example, in response to small molecules to specific mechanistic steps along this...
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| Udgivet i: | Biophys J |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355488/ https://ncbi.nlm.nih.gov/pubmed/28297646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.01.011 |
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