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Enhanced Directional Migration of Cancer Stem Cells in 3D Aligned Collagen Matrices

Directed cell migration by contact guidance in aligned collagenous extracellular matrix (ECM) is a critical enabler of breast cancer dissemination. The mechanisms of this process are poorly understood, particularly in 3D, in part because of the lack of efficient methods to generate aligned collagen...

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Publicat a:Biophys J
Autors principals: Ray, Arja, Slama, Zachary M., Morford, Rachel K., Madden, Samantha A., Provenzano, Paolo P.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355487/
https://ncbi.nlm.nih.gov/pubmed/28297639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.01.007
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