Analysis of a Compartmental Model of Endogenous Immunoglobulin G Metabolism with Application to Multiple Myeloma

Immunoglobulin G (IgG) metabolism has received much attention in the literature for two reasons: (i) IgG homeostasis is regulated by the neonatal Fc receptor (FcRn), by a pH-dependent and saturable recycling process, which presents an interesting biological system; (ii) the IgG-FcRn interaction may...

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發表在:Front Physiol
Main Authors: Kendrick, Felicity, Evans, Neil D., Arnulf, Bertrand, Avet-Loiseau, Hervé, Decaux, Olivier, Dejoie, Thomas, Fouquet, Guillemette, Guidez, Stéphanie, Harel, Stéphanie, Hebraud, Benjamin, Javaugue, Vincent, Richez, Valentine, Schraen, Susanna, Touzeau, Cyrille, Moreau, Philippe, Leleu, Xavier, Harding, Stephen, Chappell, Michael J.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Physiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355465/
https://ncbi.nlm.nih.gov/pubmed/28367126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00149
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