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Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis

Increasing evidences indicate that the abnormal DNA methylation is involved in the pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear that metylation status within HLA-DRB1 in psoriasis. Here, DNA and RNA were ob...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zong, Wenkai, Ge, Yiping, Han, Yue, Yang, Xueyuan, Li, Qi, Chen, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355347/
https://ncbi.nlm.nih.gov/pubmed/27713139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12468
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