Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

Hypoxia-ischemia (HI) can result in permanent life-long injuries such as motor and cognitive deficits. In response to cellular stressors such as hypoxia, tumor suppressor protein p53 is activated, potently initiating apoptosis and promoting Bax-dependent mitochondrial outer membrane permeabilization...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Baburamani, Ana A, Sobotka, Kristina S, Vontell, Regina, Mallard, Carina, Supramaniam, Veena G, Thornton, Claire, Hagberg, Henrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355327/
https://ncbi.nlm.nih.gov/pubmed/28076846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14518
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