Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5

Two hypomethylating agents (HMAs), azacitidine and decitabine, have demonstrated clinical activities in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML); however, potential problems include development of acquired resistance. HMA-resistant patients have very poor prognosis and this co...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Hur, Eun-Hye, Jung, Seung-Hyun, Goo, Bon-Kwan, Moon, Juhyun, Choi, Yunsuk, Choi, Dae Ro, Chung, Yeun-Jun, Lee, Je-Hwan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355301/
https://ncbi.nlm.nih.gov/pubmed/28052028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14342
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