Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia

The Gadd45a stress sensor gene is a member in the Gadd45 family of genes that includes Gadd45b & Gadd45g. To investigate the effect of GADD45A in the development of CML, syngeneic wild type lethally irradiated mice were reconstituted with either wild type or Gadd45a null myeloid progenitors tran...

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Udgivet i:Oncotarget
Main Authors: Mukherjee, Kaushiki, Sha, Xiaojin, Magimaidas, Andrew, Maifrede, Silvia, Skorski, Tomasz, Bhatia, Ravi, Hoffman, Barbara, Liebermann, Dan A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355225/
https://ncbi.nlm.nih.gov/pubmed/28086219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14580
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