Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation

Wilms’ tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. A high WT1 expression level was described in various types of human bone and soft-tissue sarcomas, including osteosarcoma (OS), but its function in carcin...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Graziano, Adriana Carol Eleonora, Cardile, Venera, Avola, Rosanna, Vicario, Nunzio, Parenti, Carmela, Salvatorelli, Lucia, Magro, Gaetano, Parenti, Rosalba
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355150/
https://ncbi.nlm.nih.gov/pubmed/28107196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14715
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