RYK promotes the stemness of glioblastoma cells via the WNT/β-catenin pathway

Glioblastoma multiforme (GBM) is characterized by a strong self-renewal potential and a poor differentiation state. Since receptor-like tyrosine kinase (RYK) activates the WNT/β-catenin pathway essential for cancer stem cell maintenance, we evaluated its contribution in conferring stemness to GBM ce...

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Udgivet i:Oncotarget
Main Authors: Adamo, Assunta, Fiore, Danilo, De Martino, Fabio, Roscigno, Giuseppina, Affinito, Alessandra, Donnarumma, Elvira, Puoti, Ilaria, Vitiani, Lucia Ricci, Pallini, Roberto, Quintavalle, Cristina, Condorelli, Gerolama
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355113/
https://ncbi.nlm.nih.gov/pubmed/28086236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14564
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