Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway

Human THUMP domain-containing protein 1 (THUMPD1) is a specific adaptor protein that modulates tRNA acetylation through interaction with NAT10. Immunohistochemical analysis of 146 breast cancer specimens (82 triple-negative and 64 non-triple-negative cases) indicated THUMPD1 expression is higher in...

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Pubblicato in:Oncotarget
Autori principali: Zhang, Xiupeng, Jiang, Guiyang, Sun, Mingfang, Zhou, Haijing, Miao, Yuan, Liang, Mengyuan, Wang, Enhua, Zhang, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355103/
https://ncbi.nlm.nih.gov/pubmed/28076326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14528
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