Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

Expression of type 5 phosphodiesterase (PDE5), a cGMP-specific hydrolytic enzyme, is frequently altered in human cancer, but its specific role in tumorigenesis remains controversial. Herein, by analyzing a cohort of 69 patients affected by glioblastoma multiforme (GBM) who underwent chemo- and radio...

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Vydáno v:Oncotarget
Hlavní autoři: Cesarini, Valeriana, Martini, Maurizio, Vitiani, Lucia Ricci, Gravina, Giovanni Luca, Agostino, Silvia Di, Graziani, Grazia, D'Alessandris, Quintino Giorgio, Pallini, Roberto, Larocca, Luigi M, Rossi, Pellegrino, Jannini, Emmanuele A, Dolci, Susanna
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355091/
https://ncbi.nlm.nih.gov/pubmed/28099939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14656
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