Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice

Chemotherapy-associated steatohepatitis is attracting increasing attention because it heralds an increased risk of morbidity and mortality in patients undergoing surgery because of liver metastases. The aim of this study was to develop in vitro and in vivo models to analyze the pathogenesis of 5-flu...

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Udgivet i:Oncotarget
Main Authors: Sommer, Judith, Mahli, Abdo, Freese, Kim, Schiergens, Tobias S., Kuecuekoktay, Fulya Suzan, Teufel, Andreas, Thasler, Wolfgang E., Müller, Martina, Bosserhoff, Anja K., Hellerbrand, Claus
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355077/
https://ncbi.nlm.nih.gov/pubmed/28055957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14371
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