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High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer
The Ca(2+)-permeable ion channel TRPM8 is a hallmark of the prostate epithelium. We recently discovered that TRPM8 is an ionotropic testosterone receptor. This finding suggested that testosterone-induced TRPM8 activity regulates Ca(2+) homeostasis in the prostate epithelium. Since androgens are sign...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355063/ https://ncbi.nlm.nih.gov/pubmed/28039451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14178 |
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