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Ipilimumab with stereotactic ablative radiation therapy: Phase I results and immunologic correlates from peripheral T-cells

PURPOSE: Little prospective data is available on clinical outcomes and immune correlates from combination radiation and immunotherapy. We conducted a phase I trial (NCT02239900) testing stereotactic ablative radiation therapy (SABR) with ipilimumab. EXPERIMENTAL DESIGN: SABR was given either concurr...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Tang, Chad, Welsh, James W., de Groot, Patricia, Massarelli, Erminia, Chang, Joe Y., Hess, Kenneth R., Basu, Sreyashi, Curran, Michael A., Cabanillas, Maria E., Subbiah, Vivek, Fu, Siqing, Tsimberidou, Apostolia M., Karp, Daniel, Gomez, Daniel R., Diab, Adi, Komaki, Ritsuko, Heymach, John, Sharma, Padmanee, Naing, Aung, Hong, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355002/
https://ncbi.nlm.nih.gov/pubmed/27649551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1432
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