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Partial lesion of the nigrostriatal dopamine pathway in rats impairs egocentric learning but not spatial learning or behavioral flexibility

Degeneration of the nigrostriatal dopaminergic system in Parkinson’s disease (PD) causes motor dysfunction and cognitive impairment, but the etiology of the cognitive deficits remains unclear. The present study investigated the behavioral effects of partial lesions of the nigrostriatal DA pathway. R...

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Détails bibliographiques
Publié dans:Behav Neurosci
Auteurs principaux: Seip-Cammack, Katharine M., Young, James J., Young, Megan E., Shapiro, Matthew L.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354943/
https://ncbi.nlm.nih.gov/pubmed/28221082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1037/bne0000189
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