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GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer
Metastasis remains the primary cause of prostate cancer (CaP)-related death. Using a genome wide shRNA screen, we identified GABARAPL1 as a potential CaP metastasis suppressor. GABARAPL1 mRNA levels inversely correlate with the invasive potential of a panel of human CaP cell lines. Lower mRNA levels...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354845/ https://ncbi.nlm.nih.gov/pubmed/27966458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13879 |
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