Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation

Current evidence suggests that oral cancer stem cells (OCSCs) possess high tumorigenic and metastatic properties as well as chemo- and radioresistance. In this study, we demonstrated that andrographolide, the main bioactive component in the medicinal plant Andrographis, significantly reduced oncogen...

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Vydáno v:Oncotarget
Hlavní autoři: Yang, Po-Yu, Hsieh, Pei-Ling, Wang, Tong Hong, Yu, Cheng-Chia, Lu, Ming-Yi, Liao, Yi-Wen, Lee, Tzu-Hsin, Peng, Chih-Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354823/
https://ncbi.nlm.nih.gov/pubmed/27926533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13755
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