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Isochaihulactone-induced DDIT3 causes ER stress-PERK independent apoptosis in glioblastoma multiforme cells

The endoplasmic reticulum (ER) is a major site of cellular homeostasis regulation. Under the ER stress condition, Glioblastoma multiform (GBM) cells activate the unfolded protein response. In this study, we discovered isochaihulactone, a natural compound extracted from the Chinese traditional herb N...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Tsai, Sheng-Feng, Tao, Michael, Ho, Li-Ing, Chiou, Tzyy-Wen, Lin, Shinn-Zong, Su, Hong-Lin, Harn, Horng-Jyh
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354812/
https://ncbi.nlm.nih.gov/pubmed/27852055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13266
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