Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells

Aberrant activation of beta-catenin/TCF is a hallmark of colon cancer. How the functions of nuclear localized beta-catenin are regulated is not fully understood. Here, it was found that FOXN3 (Forkhead box N3) was down-regulated in colon cancer tissues. Forced expression of FOXN3 inhibited the growt...

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Udgivet i:Oncotarget
Main Authors: Dai, Yuedi, Wang, Meixing, Wu, Haixia, Xiao, Mi, Liu, Houbao, Zhang, Dexiang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354770/
https://ncbi.nlm.nih.gov/pubmed/28039460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14189
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