Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability

Previous reports have shown that expression of BARD1δ, a deletion-bearing isoform of BARD1, correlates with tumor aggressiveness and progression. We show that expression of BARD1δ induces cell cycle arrest in vitro and in vivo in non-malignant cells. We investigated the mechanism that leads to proli...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pilyugin, Maxim, André, Pierre-Alain, Ratajska, Magdalena, Kuzniacka, Alina, Limon, Janusz, Tournier, Benjamin B., Colas, Julien, Laurent, Geoff, Irminger-Finger, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354735/
https://ncbi.nlm.nih.gov/pubmed/28030839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14068
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