Cyclic RGD peptide-modified liposomal drug delivery system for targeted oral apatinib administration: enhanced cellular uptake and improved therapeutic effects

Apatinib is an oral tyrosine kinase inhibitor, which selectively targets vascular endothelial growth factor receptor 2 and has the potential to treat many tumors therapeutically. Cyclic arginylglycylaspartic acid (cRGD)- and polyethylene glycol (PEG)-modified liposomes (cRGD-Lipo-PEG) were construct...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Song, Zhiwang, Lin, Yun, Zhang, Xia, Feng, Chan, Lu, Yonglin, Gao, Yong, Dong, Chunyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354530/
https://ncbi.nlm.nih.gov/pubmed/28331317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125573
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