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Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction

Human RecQ-like helicase 4 (RECQL4) plays crucial roles in replication initiation and DNA repair; however, the contextual regulation of its unwinding activity is not fully described. Mutations in RECQL4 have been linked to three diseases including Rothmund-Thomson syndrome, which is characterized by...

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Vydáno v:J Biol Chem
Hlavní autoři: Patil, Ajay Vitthal, Hsieh, Tao-Shih
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354493/
https://ncbi.nlm.nih.gov/pubmed/28159839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.764324
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