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Extracellular Loops Are Essential for the Assembly and Function of Polycystin Receptor-Ion Channel Complexes

Polycystin complexes, or TRPP-PKD complexes, made of transient receptor potential channel polycystin (TRPP) and polycystic kidney disease (PKD) proteins, play key roles in coupling extracellular stimuli with intracellular Ca(2+) signals. For example, the TRPP2-PKD1 complex has a crucial function in...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Salehi-Najafabadi, Zahra, Li, Bin, Valentino, Victoria, Ng, Courtney, Martin, Hannah, Yu, Yang, Wang, Zhifei, Kashyap, Parul, Yu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354480/
https://ncbi.nlm.nih.gov/pubmed/28154010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767897
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