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Extracellular Loops Are Essential for the Assembly and Function of Polycystin Receptor-Ion Channel Complexes
Polycystin complexes, or TRPP-PKD complexes, made of transient receptor potential channel polycystin (TRPP) and polycystic kidney disease (PKD) proteins, play key roles in coupling extracellular stimuli with intracellular Ca(2+) signals. For example, the TRPP2-PKD1 complex has a crucial function in...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354480/ https://ncbi.nlm.nih.gov/pubmed/28154010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767897 |
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