Integrated analysis of promoter mutation, methylation and expression of AKT1 gene in Chinese breast cancer patients

BACKGROUND: As downstream mediators of PI3K /PTEN /AKT /mTORC1 pathway, the AKT isoforms play critical roles in tumorgenesis. Although the pleiotropic effects of AKT1 in breast cancer have been reported, the genetic and epigenetic characteristics of AKT1 promoter region in breast cancer remains to b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Heng, Jianfu, Guo, Xinwu, Wu, Wenhan, Wang, Yue, Li, Guoli, Chen, Ming, Peng, Limin, Wang, Shouman, Dai, Lizhong, Tang, Lili, Wang, Jun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354459/
https://ncbi.nlm.nih.gov/pubmed/28301567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174022
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia