Dengue virus genomic variation associated with mosquito adaptation defines the pattern of viral non-coding RNAs and fitness in human cells

The Flavivirus genus includes a large number of medically relevant pathogens that cycle between humans and arthropods. This host alternation imposes a selective pressure on the viral population. Here, we found that dengue virus, the most important viral human pathogen transmitted by insects, evolved...

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Udgivet i:PLoS Pathog
Main Authors: Filomatori, Claudia V., Carballeda, Juan M., Villordo, Sergio M., Aguirre, Sebastian, Pallarés, Horacio M., Maestre, Ana M., Sánchez-Vargas, Irma, Blair, Carol D., Fabri, Cintia, Morales, Maria A., Fernandez-Sesma, Ana, Gamarnik, Andrea V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354447/
https://ncbi.nlm.nih.gov/pubmed/28264033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006265
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