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Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele
Tyrosine kinase-activating mutations in Met have been observed in hereditary papillary renal carcinomas as well as in other cancers. These mutations have been examined in several in vitro systems, where they cause constitutive Met activation, focus formation, and cell motility, and are tumorigenic i...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535398/ https://ncbi.nlm.nih.gov/pubmed/15557554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407651101 |
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