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Tumor-infiltrating CD39(+) γδTregs are novel immunosuppressive T cells in human colorectal cancer

Tumor microenvironment (TME) promotes immune suppression through recruiting and expanding suppressive immune cells such as regulatory T cells (Tregs) to facilitate cancer progression. In this study, we identify a novel CD39(+) γδTreg in human colorectal cancer (CRC). CD39(+) γδTregs are the predomin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Hu, Guoming, Wu, Pin, Cheng, Pu, Zhang, Zhigang, Wang, Zhen, Yu, Xiuyan, Shao, Xuan, Wu, Dang, Ye, Jun, Zhang, Tao, Wang, Xiaochen, Qiu, Fuming, Yan, Jun, Huang, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353931/
https://ncbi.nlm.nih.gov/pubmed/28344891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1277305
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