Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina

Early development of the lens and retina depends upon reciprocal inductive interactions between the embryonic surface ectoderm and the underlying neuroepithelium of the optic vesicle. FGF signaling has been implicated in this signal exchange. The docking protein FRS2α is a major mediator of FGF sign...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Gotoh, N., Ito, M., Yamamoto, S., Yoshino, I., Song, N., Wang, Y., Lax, I., Schlessinger, J., Shibuya, M., Lang, R. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15569927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407577101
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